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Submission Preparation Checklist

As part of the submission process, authors are required to check off their submission's compliance with all of the following items, and submissions may be returned to authors that do not adhere to these guidelines.
  • The submission has not been previously published, nor is it before another journal for consideration (or an explanation has been provided in Comments to the Editor).
  • The submission file is in OpenOffice, Microsoft Word, or RTF document file format.
  • Where available, URLs for the references have been provided.
  • The text is single-spaced; uses a 12-point font; employs italics, rather than underlining (except with URL addresses); and all illustrations, figures, and tables are placed within the text at the appropriate points, rather than at the end.
  • The text adheres to the stylistic and bibliographic requirements outlined in the Author Guidelines.

Author Guidelines


Please read and follow these instructions carefully; doing so will ensure that the publication of your manuscript is as rapid and efficient as possible. The Publisher reserves the right to return manuscripts that are not prepared in accordance with these instructions.


The goal of the “American Journal of Translational Medicine (AJTM)” is to publish peer-reviewed papers that identify and fill scientific knowledge gaps at the junction of basic research and human applications. Our journal publishes articles focusing on information derived from human experimentation so as to optimize the communication between basic and clinical science. The original research published in our journal should report significant progress toward the prevention, diagnosis, or treatment of disease; transform our understanding of human biology. These papers preferably will provide insights and evidence with influence beyond their own fields of research. Finally, we will publish papers that meet rigorous criteria of excellence and innovation,

The journal covers all areas of translational medicine but has several special areas:

1. Cancer early finding and diagnosis, Cancer microenvironment,

2. Cancer treatment, Cancer epigenetics,

3. Cardiovascular, Metabolic and Lipoprotein Translation,

4. Cell, tissue and gene therapy, Stem cell therapy,

5. Clinical translation, Disease biomarkers,

6. Immunobiology and Immunotherapy,

7. Infectious disease, such as COVID-19

8. Medical Bioinformatics, Neuroscience,

9. Nutrition & metabolism,

10. Patient-targeted molecular therapies in adult and/or child,

11. Reproduction and health,

12. Signal transduction in development and differentiation

13. Tissue engineering and regeneration medicine

We are interested in the manuscript which include experimental or clinical investigation, both laboratory and translational study. We are interested in the manuscript, which cover studies at the molecular, cellular, organ and organism levels. It can be either animal or human studies.

Submission of manuscripts

Authors should submit Word or rich-text files by email to or to submit your manuscript online, please use the following link: License (Copyright) and permissions

It is a condition of publication that authors grant an exclusive license to HGI Journals. This ensures that requests from third parties to reproduce articles are handled efficiently and consistently, and will also allow the article to be as widely disseminated as possible. In assigning copyright, authors may use their own material in other publications, provided that the journal is acknowledged as the original place of publication, and HGI Journals is notified in writing and in advance.

Work submitted for publication must be original, previously unpublished, and not under consideration for publication elsewhere. If previously published figures, tables, or parts of text are to be included, the copyright-holder’s permission must have been obtained prior to submission.

Cover Letter

All submissions should be accompanied by a cover letter that includes a brief overview of the manuscript and the corresponding and contacting author contact information including full name, e-mail address, phone number, and mailing address (corresponding author and contacting author). It should also specify the number of display items (figures and tables), the number of attachments (manuscript, figures, Supplementary Information if any), and their formats.

It must include a statement indicating that the article has not been published in another publication and is not being submitted simultaneously to another journal.

Preparation of the manuscript

General: Papers must be clearly written in English. If you would like additional help with the quality of your written English, including grammar, spelling, and language usage consult American Journal Expert ( The format of different types of articles is as under:

Research Articles

Research articles present original research and address a clearly stated specific hypothesis or question. Papers should provide novel approaches and new insights into the problem addressed. A research article should divide into the following headings:

Title page/Author's information/Present address/Abstract/Keywords/Introduction/Materials and Methods/Results/Discussion/Acknowledgments/References/Tables/Figures

It should be no more than 6000 words, and could include 8 figures and 4 tables. Abstract should not be over 300 words.


Review articles are an attempt by one or more authors to sum up the current state of the research on a particular topic. Ideally, the author searches for everything relevant to the topic, and then sorts it all out into a coherent view of the "state of the art" as it now stands. Interested scientists may write their review articles under the following headings:

Title page/Author's information/Keywords/Present address/Abstract/ Text/Acknowledgments/References/Tables/Figures

It should be no more than 8000 words, and could include 6 figures and 3 tables.

Short Communications (or Brief report)

A short communication is for a concise, but independent report representing a significant contribution.

Short communication is not intended to publish preliminary results.

It should be no more than 2500 words, and could include two figures or tables. It should have at least 8 references. Scientists may prepare their short communications under the following headings:

Title page/Author's information/Present address/Abstract/Keywords/Introduction/Materials and Methods/Results/Discussion/Acknowledgments/References/Tables/Figures/


Editorials are short, invited opinion pieces that discuss an issue of immediate importance to the research community. Editorials should have fewer than 1000 words total, no abstract, a minimal number of references (definitely no more than 5), and no figures or tables (although they do have a photograph of the author as an illustration).


Focus articles are short, timely pieces that spotlight either recent research findings or policy issues related to research (for example, regulatory, funding, educational, or legislative discussions). Focus articles should not exceed 2500 words total (including abstract, main text, references and figure legend). They should have a short pithy title, a one-sentence abstract, no more than 10 references, and one figure (with figure legend) or table.


Commentaries present in-depth analysis of current issues such as policy, funding, regulatory, educational, and legislative issues, new institutes, careers etc. Commentaries should not exceed 3000 words total (including abstract, main text, references and figure legends). They should have a short pithy title, an abstract of 150 words or less, no more than 35 references, and one or two figures (with figure legends) or tables.


Perspectives discuss one or a cluster of recently published papers or a current research topic of high interest in which an author's perspective sheds an incisive light on key findings in research. These articles typically have one or two authors whose task is to inform our interdisciplinary readership about exciting scientific developments in the author's area of expertise. Other appropriate topics include discussions of methods, books, or meeting highlights.

Perspectives present a new and unique viewpoint on existing problems, fundamental concepts, or prevalent notions on a specific topic, propose and support a new hypothesis, or discuss the implications of a newly implemented innovation. Perspective pieces may focus on current advances and future directions on a topic, and may include original data as well as personal opinion.

Perspectives are usually between 2000 and 4000 words total (including abstract, main text, references and figure legends). They should have a short pithy title, an abstract of 150 words or less, no more than 35 references, and 1 or 2 figures (with figure legends) or tables. These are usually short peer-reviewed articles.

Case report

Case reports may provide a brief description of up to four cases of a particular condition that is unusual and also provides new insights into diagnosis or clinical management. AJTM especially welcomes following types of case reports: Unusual clinical disorder/disease presentation; Unusual associations between clinical disorders and signs & symptoms; Unexpected findings during treatment; Unexpected or rare adverse drug effects or interactions; Studies on novel procedure/diagnostic techniques; Rare diseases presentations and management; New infections or disease outbreak in local community; Clinically significant images. Case

Reports should be a maximum of 1,500 words with no more than four tables or figures and 15 references.

Publication of any personal information about an identifiable living patient requires the explicit consent of the patient or guardian. This is a requirement under the UK’s Data Protection legislation. We expect authors to use the latest BMJ consent form, which is available in several languages.

Patient consent: You must have signed informed consent from patients (or guardians) before submitting to AJTM. Please anonymise the patient’s details as much as possible, eg, specific ages, ethnicity, occupations.

For living patients this is a legal requirement and we will not send your article for review without explicit consent from the patient or guardian.

If the patient is dead the USA Data Protection Act does not apply, but the authors must seek permission from a relative (ideally the next of kin). If you don’t have signed consent from a deceased patient, guardian or family, the head of your medical team/hospital or legal team must take responsibility that exhaustive attempts have been made to contact the family and that the paper has been sufficiently anonymised not to cause harm to the patient’s family.

Letter to the Editor

A letter to the Editor is a brief report that is within the journal's scope and of particular interest to the community, but not suitable as a standard research article.

A letter to the editor generally takes one of the following forms:

A: A substantial re-analysis of a previously published article in AJTM or in another journal.

B: An article that may not cover 'standard research' but that is of general interest to the broad readership of American Journal of Translational Medicine

A maximum of ten articles may be included in the references.

Length of article: A letter to the Editor should be between 600 to 1500 words.

It could include two figures or tables. Scientists may prepare their short communications under the following headings:

Title page/Author(s) name and Affiliations/Abstract/Key Words/Main text/Correspondence/List of abbreviations used (if any)/Competing interests/Authors' contributions/Acknowledgements and Funding/ References/Tables and captions (if any)/Illustrations and Figures/Figure legends (if any)

Letters to the Editor may be edited for clarity or length and may be subject to peer review at the Editors' discretion. To contribute, please contact the Editors.

Systematic reviews and meta-analyses

A systematic review paper, as defined by The Cochrane Collaboration, is a review of a clearly formulated question that uses explicit, systematic methods to identify, select, and critically appraise relevant research, and to collect and analyze data from the studies that are included in the review. These reviews differ substantially from narrative-based reviews or synthesis articles. Statistical methods (meta-analysis) may or may not be used to analyze and summarize the results of the included studies.

Reports of systematic reviews and meta-analyses must include a completed PRISMA (Preferred Reporting

Items for Systematic Reviews and Meta-Analyses) checklist and flow diagram to accompany the main text. You may download the blanc template in our website in Author guide portion.

Authors must also state in their “Methods” section whether a protocol exists for their systematic review, and if so, provide a copy of the protocol as supporting information and provide the registry number in the abstract.

If your article is a systematic review or a meta-analysis you should:

State this in your cover letter

Select “Research Article” as your article type when submitting

Include the PRISMA flow diagram as Figure 1 (required where applicable)

Include the PRISMA checklist as supporting information

Meta-analysis of genetic association studies

Manuscripts reporting a meta-analysis of genetic association studies must report results of value to the field and should be reported according to the guidelines presented in Systematic Reviews of Genetic Association Studies by Sagoo et al.

On submission, authors will be asked to justify the rationale for the meta-analysis and how it contributes to the base of scientific knowledge in the light of previously published results. Authors will also be asked to complete a checklist (DOCX) outlining information about the justification for the study and the methodology employed.

Meta-analyses that replicate published studies will be rejected if the authors do not provide adequate justification.

Personal data from third-party sources

For all studies using personal data from internet-based and other third-party sources (e.g., social media, blogs,

other internet sources, mobile phone companies), data must be collected and used according to company/website Terms and Conditions, with appropriate permissions. All data sources must be acknowledged clearly in the Materials and Methods section.

Conference/Meeting Abstract Proceedings

We also publish the proceedings from international conferences or selected abstract presented at a meeting. All enquiries regarding the possible publication of Meeting Proceedings in AJTM should be sent to the Editor via

the Editorial offices at

News and Views

News and Views contain updates and newsworthy discussion pieces relevant to the journal's scope. All enquiries regarding the possible publication of News and Views should be sent to the Editor via the Editorial offices at


Tables must be numbered with Arabic numerals in the order in which they are cited in the text. They should have a brief descriptive title placed at the top. A short description is also accepted. Footnotes can be included below the table. Tables cannot duplicate data contained in the text. Tables must be sent in Microsoft Word and have no links to the main document or other archives. Provide files at approximately the correct size they are to be printed (letter size). Please submit tables as editable text and not as images. Tables can be placed either next to the relevant text in the article, or on separate page(s) at the end. Number tables consecutively in accordance with their appearance in the text and place any table notes below the table body. Be sparing in the use of tables and ensure that the data presented in them do not duplicate results described elsewhere in the article. Please avoid using vertical rules.


Figures should be supplied in an electronic format at a suitable size for printing with the following resolutions:

600 dots per inch (dpi) for line drawings and combinations; 300 dpi for greyscale and color. Color figures must be supplied in CMYK not RGB colors. Please ensure that the prepared electronic image files print at a legible size and are of a high quality for publication. Figure captions: Ensure that each illustration has a caption.

A caption should comprise a brief title (not on the figure itself) and a description of the illustration. Keep text in the illustrations themselves to a minimum but explain all symbols and abbreviations used.

Regulation in using a reproduced figure or table

A. Are you using a reproduced figure or table?

A reproduced figure or table is an exact copy of a figure or table that has already been published by a journal or book, both in print and online. The figure may be one that was published in your manuscript, or it may be from another researcher’s manuscript. A reproduced figure or table is not an original. To use a reproduced figure or table in a manuscript, you must receive permission from the owner of the copyright of the original figure or table, and you must also include attribution to the original source in your manuscript next to the reproduced figure or table. The owner of the copyright will often be the publisher of the original figure or table. In some journals, such as Endocrine Society journals, figures and tables used in most types of article may not be reproduced or adapted; only in reviews and mini-reviews may reproduced or adapted figures and tables be used.

B. Are you using an adapted figure or table?

An adapted figure or table is one that looks similar to a figure or table that has been previously published but has been changed slightly. To use an adapted figure or table in your manuscript, you must also obtain permission from the copyright owner (usually the original publisher) and provide attribution to the source that published the original figure or table. This must be done even if you created the original figure or table from which the new one has been adapted.

C. Suggestion to authors

AJTM recommend authors to avoid in using a reproduced figure or table when the authors are writing the review article to publish in AJTM


At the end of the paper, in the References section the literature should be arranged in alphabetical order. If they have the same author, they should be in chronological order. In the text: References must be cited in the text mentioning the last name of the author and year between parentheses. In case of two authors, both should be mentioned. When there are three or more authors, mention only the first author followed by et al. When two or more references are cited in the same parenthesis, the authors should be in chronological order. And if they have the same year, they should be in alphabetical order.

Moreover, if there is more than one reference of the same author and the same year, they should be indicated with letters.

Article-processing charges

American Journal of Translational Medicine levies an article-processing charge for each article accepted for publication

Submission fee: Starting July 1st, 2020, the American Journal of Translational Medicine will require authors

submission fee from $50 for each submission. Submission fee is non-refundable and a paper may be rejected by the Editors without being sent for review. The submission fees are used to support journal related activities.

Page charges: Authors whose research was supported by grants, special funds (including departmental and institutional), or contracts (including governmental) or whose research was done as part of their official duties (government or corporate, etc.) are required to pay page charges (based on the number of typeset pages, including illustrations, in the article).

Corresponding authors of articles accepted for publication will receive an e-mail notifying them how to pay page and any other applicable publication charges (see below).

Page charges are $750 per article (Research article or Review article) in 2021

If the research was not supported by any of the means described above, a request to reduce or waive the charges may be sent to the Editor, American Journal of Translational Medicine, PO Box 37974, Honolulu, HI 96837. USA. (e-mail  [after acceptance of the manuscript]). The request must include the manuscript control number assigned by AJTM and indicate how the work was supported. Waivers apply only to page charges; responsibility for color charges and other publication fees remains with the author. Commentaries are not subject to page charges. Color charges: The cost of publishing in color must be borne by the author. Color charges are $150 per color figure (subject to change without notice). Commentaries are not subject to color charges. However, these charges may be reduced or waived if the Editor finds the difficulty from authors in this regard.

Language edition

Before publication, the journal will arrange English language edition for the accepted manuscript which authors are not native English speakers and the manuscript has been identified to be needed for language edition by peer-reviewers or editors. Authors are required to pay this cost for English Language edition


All manuscripts will undergo some editorial modification, so it is important to check proofs carefully. PDF page proofs will be sent via e-mail to the corresponding author for checking. To avoid delays in publication, proofs should be checked and returned within 48 hours. Corrections should be returned by annotated PDF, e-mail or fax. Extensive changes to the text may be charged to the author.

Post-production corrections

Corrections are made if the publication record is seriously affected by the academic accuracy of published information. Where these amendments concern peer-reviewed material, the correction will be published as a formal notice (erratum) in a subsequent issue.

Changes to authorship

Authors are expected to consider carefully the list and order of authors before submitting their manuscript and provide the definitive list of authors at the time of the original submission. Any addition, deletion or rearrangement of author names in the authorship list should be made only before the manuscript has been accepted and only if approved by the journal Editor. To request such a change, the Editor must receive the following from the corresponding author: (a) the reason for the change in author list and (b) written confirmation (e-mail, letter) from all authors that they agree with the addition, removal or rearrangement. In the case of addition or removal of authors, this includes confirmation from the author being added or removed.

Only in exceptional circumstances will the Editor consider the addition, deletion or rearrangement of authors after the manuscript has been accepted. While the Editor considers the request, publication of the manuscript will be suspended. If the manuscript has already been published in an online issue, any requests approved by the Editor will result in a corrigendum.


Accepted peer-reviewed original articles, short communication and review, Case report, Commentary, News and View etc., will be published both electronical and hard print.

Journal Cover Figures

Authors are invited to submit scientifically interesting and visually arresting cover images (see our archive).

Illustrations need not appear in the article but should be representative of the work. Images should be original, and authors grant AJTM a license to publish. Include a brief lay-language caption (50–60 words) and credit information (e.g., Image courtesy of...). Images should be 21 cm wide by 22.5 cm high. Files should be EPS or TIFF and should be in RGB color mode. Cover figure files may be submitted online when the paper is submitted or may be sent to; contact AJTM for instructions on submitting large files. The deadline for cover submissions is when proof corrections are returned. Submissions provided outside the online submission system should include the manuscript number, author name, phone, and email.

Manuscript submission online:

To submit your manuscript online, please use the following link:


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